Warning: require_once(): It is not safe to rely on the system's timezone settings. You are *required* to use the date.timezone setting or the date_default_timezone_set() function. In case you used any of those methods and you are still getting this warning, you most likely misspelled the timezone identifier. We selected the timezone 'UTC' for now, but please set date.timezone to select your timezone. in /home/gkatak/public_html/TNBC_EGFR_SUPPLEMENTAL_TABLES/.excel/excel_reader2.php on line 916

Deprecated: Assigning the return value of new by reference is deprecated in /home/gkatak/public_html/TNBC_EGFR_SUPPLEMENTAL_TABLES/.excel/excel_reader2.php on line 916
  A B C D E F
1            
2   Table S3: Associations between EGFR parameters    
3            
4     EGFR IHC  
5     Negative (N=161) Positive (N=185) Total (N=346) p-value
6   EGFR FISH*
7   Negative 103 (38.58%) 154 (57.68%) 257 (96.25%) 0.055
8   Positive 1 (0.37%) 9 (3.37%) 10 (3.75%)  
9   Total 104 (38.95%) 163 (61.05%) 267 (100.0%)  
10   EGFR copies; cut off 2.62
11   Low 52 (32.3%) 68 (36.8%) 130 (37.6%) 0.21
12   High 52 (32.3%) 95 (51.3%) 147 (42.4%)  
13   Total 104 (64.6%) 163 (88.1%) 267 (77.2%)  
14   CEN7 copies; cut off 2.65
15   Low 48 (29.8%) 69 (37.3%) 117 (33.8%) 0.61
16   High 56 (34.8%) 94 (50.1%) 150 (43.4%)  
17   Total 104 (64.6%) 163 (88.1%) 267 (77.2%)  
18   EGFR mRNA^
19   Low 59 (33.71%) 73 (41.71%) 132 (75.43%) <0.001
20   High 4 (2.29%) 39 (22.29%) 43 (24.57%)  
21   Total 63 (36.0%) 112 (64.0%) 175 (100.0%)  
22   EGFR mutations
23   Mutant 8 (3.02%) 4 (1.51%) 12 (4.53%) 0.10
24   Non-mutant 108 (40.75%) 145 (54.72%) 253 (95.47%)  
25   Total 116 (43.77%) 149 (56.23%) 265 (100.0%)  
26   *: EGFR/CEN7 ratio≥2.0 or ratio<2 and copies > 6; ^: 75% cutoff;
27