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PNUMBER TUBE_March2012 AGE Randomization group Menopausal status Tumor grade Type of surgery n. of Positive nodes Tumor size (cm) Histology Receptor status ESR1 amplification ESR1 gene copies CEN6 copies ESR1/CEN6 ratio Clusters
10965 611 77 E-T-CMF post III Breast conserving surgery 3 4.2 Invasive ductal positive Gain (>1-<2) 3.68 2.9 1.27 no cluster